I am a
Home I AM A Search Login

Papers of the Week

2020 Jan-Dec

Allergy Rhinol (Providence)


Extramedullary Hematopoiesis in the Sinonasal Cavity: A Case Report and Review of the Literature.


Clark CA, Worden CP, Thorp BD, Ebert CS, Zanation AM, Senior BA, M Johnson S, McClain WG, Kimple AJ
Allergy Rhinol (Providence). 2020 Jan-Dec; 11:2152656720918874.
PMID: 32363047.


Extramedullary hematopoiesis (EMH) occurs in patients with hematologic disorders, but rarely within the paranasal sinuses. We report a case of EMH in a 17-year-old male with sickle cell disease (SCD) who presented with occipital pain and sinusitis. A computed tomography (CT) scan demonstrated heterogeneous opacification of the right maxillary sinus concerning for allergic fungal sinusitis or a fungal ball with bony erosion. He was taken to the operating room for endoscopic biopsy and a limited endoscopic sinus surgery. Grossly, his maxillary sinus was filled with spiculated osseous tissue. Final pathology demonstrated active hematopoietic bone marrow filling the sinus.