I am a
Home I AM A Search Login

Papers of the Week

2020 May 03

Eur J Clin Pharmacol

Single dose epidural hydromorphone in labour pain: maternal pharmacokinetics and neonatal exposure.


Puhto T, Kokki M, Hakomäki H, Spalding M, Gunnar T, Alahuhta S, Vakkala M
Eur J Clin Pharmacol. 2020 May 03.
PMID: 32363420.


Epidural hydromorphone could be useful in obstetric analgesia as there is a need for a more water-soluble opioid than sufentanil or fentanyl with prolonged analgesic effect. To our knowledge, the pharmacokinetics of epidural hydromorphone has not been evaluated in parturients.