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Papers of the Week


2020 May 03


Eur J Clin Pharmacol

Single dose epidural hydromorphone in labour pain: maternal pharmacokinetics and neonatal exposure.

Authors

Puhto T, Kokki M, Hakomäki H, Spalding M, Gunnar T, Alahuhta S, Vakkala M
Eur J Clin Pharmacol. 2020 May 03.
PMID: 32363420.

Abstract

Epidural hydromorphone could be useful in obstetric analgesia as there is a need for a more water-soluble opioid than sufentanil or fentanyl with prolonged analgesic effect. To our knowledge, the pharmacokinetics of epidural hydromorphone has not been evaluated in parturients.