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Papers of the Week


2020 May 04


Psychopharmacology (Berl)

Gelsemine, a natural alkaloid extracted from Gelsemium elegans Benth. alleviates neuroinflammation and cognitive impairments in Aβ oligomer-treated mice.

Authors

Chen L, Pan H, Bai Y, Li H, Yang W, Lin Z-X, Cui W, Xian Y-F
Psychopharmacology (Berl). 2020 May 04.
PMID: 32363440.

Abstract

Gelsemine is a natural alkaloid extracted from Gelsemium elegans Benth., a traditional Chinese medicinal herb. Gelsemine has been shown to penetrate the brain, and could produce neurological activities, such as anxiolytic and neuralgia-alleviating effects, suggesting that this natural compound might be used for treating nervous system diseases.