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Papers of the Week

2020 Apr 30

Br J Clin Pharmacol

Safety and Pharmacokinetic Profiles of MGS0274 Besylate (TS-134), a Novel Metabotropic Glutamate 2/3 Receptor Agonist Prodrug, in Healthy Subjects.


Watanabe M, Marcy B, Kinoshita K, Fukasawa M, Hikichi H, Chaki S, Okuyama S, Gevorkyan H, Yoshida S
Br J Clin Pharmacol. 2020 Apr 30.
PMID: 32353162.


The safety and pharmacokinetics of single and multiple doses of a novel mGlu receptor agonist prodrug, MGS0274 besylate (TS-134), were investigated in healthy subjects.