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Papers of the Week

2020 Apr 27

J Eur Acad Dermatol Venereol

Effectiveness and adverse events of ivermectin treatment for scabies in 30 infant patients: Report from a German single center.


Ständer S, Kirschstein DJ, Kohl-Sobania M, Zillikens D, Ludwig RJ, Anemüller W
J Eur Acad Dermatol Venereol. 2020 Apr 27.
PMID: 32339346.


Scabies is a globally prevalent parasitic skin infestation characterized by severe pruritus and a heterogeneous clinical picture depending on the immune status of the individual. Epidemiologic studies reveal a higher susceptibility for young, old and, in general, immunocompromised individuals. Disease-related morbidity and secondary complications due to a disrupted epidermal barrier, e.g. subsequent bacterial infections and chronic kidney disease, further add to the patients´ burden . With current treatment options, induction of remission is achieved in most of the patients. Specifically, the oral administration of ivermectin has substantially decreased the prevalence of scabies in communities and has proven to be effective and tolerable .