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Papers of the Week


2020 Apr 22


J Trauma Acute Care Surg

Reperfusion Repercussions: A Review of the Metabolic Derangements following Resuscitative Endovascular Balloon Occlusion of the Aorta.

Authors

Abid M, Neff L, Russo R, Williams T, Hoareau G, Grayson JK, DuBose J, Lendrum R, Johnson AM
J Trauma Acute Care Surg. 2020 Apr 22.
PMID: 32332257.

Abstract

Current Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) literature focuses on improving outcomes through careful patient selection, diligent catheter placement, and expeditious definitive hemorrhage control. However, the detection and treatment of post-REBOA ischemia-reperfusion injury (IRI) remains an area for potential improvement. Herein we provide a review of the metabolic derangements that we have encountered while managing post-REBOA IRI in past swine experiments. We also provide data-driven clinical recommendations to facilitate resuscitation post-REBOA deflation that may be translatable to humans.