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Papers of the Week

Papers: 25 Apr 2020 - 1 May 2020

Human Studies

2020 Apr 23


The Pathways and Processes Underlying Spinal Transmission of Low Back Pain: Observations From Dorsal Root Ganglion Stimulation Treatment.


Chapman KB, Groenen PS, Vissers KC, van Helmond N, Stanton-Hicks MD
Neuromodulation. 2020 Apr 23.
PMID: 32329155.


Dorsal root ganglion stimulation (DRG-S) is a novel approach to treat chronic pain. Lead placement at L2 has been reported to be an effective treatment for axial low back pain (LBP) primarily of discogenic etiology. We have recently shown, in a diverse cohort including cases of multilevel instrumentation following extensive prior back surgeries, that DRG-S lead placement at T12 is another promising target. Local effects at the T12 DRG, alone, are insufficient to explain these results.