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Papers of the Week

2020 Apr 24

Lasers Surg Med

Photobiomodulation Therapy is Able to Modulate PGE Levels in Patients With Chronic Non-Specific Low Back Pain: A Randomized Placebo-Controlled Trial.


Tomazoni SS, Costa L O, Joensen J, Stausholm MB, Naterstad IF, Ernberg M, Leal-Junior E CP, Bjordal JM
Lasers Surg Med. 2020 Apr 24.
PMID: 32330315.


Non-specific low back pain (LBP) is responsible for triggering increased biomarkers levels. In this way, photobiomodulation therapy (PBMT) may be an interesting alternative to treat these patients. One of the possible biological mechanisms of PBMT involved to decrease pain intensity in patients with musculoskeletal disorders is modulation of the inflammatory mediators' levels. The aim of this study was to evaluate the effects of PBMT compared with placebo on inflammatory mediators' levels and pain intensity in patients with chronic non-specific LBP.