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Papers of the Week

2020 Apr 22

BMJ Support Palliat Care

Methadone rotation for cancer pain: an observational study.


Tan C, Wong J F, Yee C M, Hum A
BMJ Support Palliat Care. 2020 Apr 22.
PMID: 32321728.


Methadone is a useful option in the treatment of cancer pain. Despite its advantages, methadone use is complicated due to high interindividual variability in pharmacokinetics. Various rotation methods from other opioids have been proposed in mostly Caucasian populations.