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Papers of the Week


2020 Apr 22


BMJ Support Palliat Care

Methadone rotation for cancer pain: an observational study.

Authors

Tan C, Wong J F, Yee C M, Hum A
BMJ Support Palliat Care. 2020 Apr 22.
PMID: 32321728.

Abstract

Methadone is a useful option in the treatment of cancer pain. Despite its advantages, methadone use is complicated due to high interindividual variability in pharmacokinetics. Various rotation methods from other opioids have been proposed in mostly Caucasian populations.