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Papers of the Week

2020 Apr 17

Magn Reson Med Sci

Direct Impact of Motor Cortical Stimulation on the Blood Oxygen-level Dependent Response in Rats.


Xin Z, Abe Y, Liu S, Tanaka KF, Hosomi K, Saitoh Y, Sekino M
Magn Reson Med Sci. 2020 Apr 17.
PMID: 32307360.


Neuropathic pain is a complex and distressing chronic illness in modern medicine. Since 1990s, motor cortex stimulation (MCS) has emerged as a potential treatment for chronic neuropathic pain; however, the precise mechanisms underlying analgesia induced by MCS are not completely understood. The purpose of the present study was to investigate the blood oxygen-level dependent (BOLD) response in the brain during MCS.