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Papers of the Week


2020


PLoS One


15


4

Amitriptyline prescribing in public sector healthcare facilities in the Western Cape, South Africa.

Authors

Coetzee R, Johnson Y, van Niekerk J, Namane M
PLoS One. 2020; 15(4):e0231675.
PMID: 32311002.

Abstract

Inappropriate medication use is a major patient safety concern, especially for the elderly population. Amitriptyline is widely used in primary care in South Africa and a cross-sectional study found that amitriptyline was prescribed potentially inappropriately in 6.5% of elderly patients. An analysis of prescriptions from the Chronic Dispensing Unit in the Western Cape revealed that amitriptyline was one of the most common medicines prescribed without a suitable diagnosis listed on the prescription.