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2020 Apr 13
Cell Mol Gastroenterol Hepatol
Mitochondria exist in a constantly remodelling network, and excessive fragmentation can be pathophysiological. Mitochondrial dysfunction can accompany enteric inflammation, but any contribution of altered mitochondrial dynamics (i.e. fission/fusion) to gut inflammation is unknown. We hypothesised that perturbed mitochondrial dynamics would contribute to colitis.