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Papers of the Week

Papers: 11 Apr 2020 - 17 Apr 2020

Pharmacology/Drug Development

2020 May

Phys Med Rehabil Clin N Am



Nonsteroidal Antiinflammatory Drugs for Acute and Chronic Pain.


Atkinson TJ, Fudin J
Phys Med Rehabil Clin N Am. 2020 May; 31(2):219-231.
PMID: 32279725.


Understanding nonsteroidal antiinflammatory drug (NSAID) use and impact on common rheumatic and arthritic conditions is critical to reconciling their appropriate use with their potentially serious adverse effects. NSAIDs have a profound impact on the treatment of connective tissue disorders because of their ability to address the underlying cause with specific benefits of decreasing stiffness and inflammation, and improving mobility. NSAID use is twice as common as opioid use, and inappropriate use of NSAIDs is widespread. NSAID use should be monitored and the impact understood to mitigate the risks. NSAID discontinuation should be evidence based and individualized to specific requirements.