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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Mechanisms of the antiplatelet and analgesic effects of dextromethorphan and its metabolites.

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2019 Apr-Jun


Ci Ji Yi Xue Za Zhi


http://www.ncbi.nlm.nih.gov/pubmed/32269947?dopt=Abstract


32


2

Mechanisms of the antiplatelet and analgesic effects of dextromethorphan and its metabolites.

Authors

Mechanisms of the antiplatelet and analgesic effects of dextromethorphan and its metabolites.
Su W-L, Weng Y-Y, Huang W-H, Shui H-A, Chou T-C
Ci Ji Yi Xue Za Zhi. 2019 Apr-Jun; 32(2):154-161.
PMID: 32269947.

Abstract

In the present study, we investigated the effects of dextromethorphan (DM) and its metabolites, including dextrorphan (LK2), 3-methoxymorphinan (LK3), and 3-hydroxymorphinan (LK4), on platelet aggregation and the inflammatory pain caused by carrageenan in rats, and their underlying mechanisms.
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