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Papers of the Week

Papers: 4 Apr 2020 - 10 Apr 2020


Animal Studies

2020 Apr 07


Abnormal gut microbiota composition is associated with experimental autoimmune prostatitis-induced depressive-like behaviors in mice.


Du H-X, Liu Y, Zhang L-G, Zhan C-S, Chen J, Zhang M, Chen X-G, Zhang L, Liang C-zhao
Prostate. 2020 Apr 07.
PMID: 32255522.


Depressive symptoms are found in approximately 78% of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) patients, but the pathological mechanisms remain unknown. Increasing evidence suggests that abnormal gut microbiota may play an important role in depression. Thus, we aimed to investigate whether gut microbiota contributes to CP/CPPS-associated depression by using a mouse model of experimental autoimmune prostatitis (EAP).