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Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract. Surgery is the cornerstone of its treatment, although during the last ten years the administration of tyrosine kinase inhibitors (TKI) has become an essential tool as a neoadjuvant and adjuvant strategy in non-wild type GIST. Previous experience has shown that when liver resection is not feasible, liver transplantation (LT) can be considered, although it has not been considered a standard indication for cadaveric LT listing.