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Papers of the Week

2020 Apr 04

Liver Transpl

First Report of Living Donor Liver Transplantation for Imatinib-Resistant GIST Liver Metastases. A new therapeutic option in Transplant Oncology.


Benítez C, Inzunza M, Riveros S, Rivas V, Garrido M, Dib M, Barrera F, Arab JP, Torres J, I Cortinez L, Briceño E, Guerra JF, Fernandes E, Martínez JA
Liver Transpl. 2020 Apr 04.
PMID: 32246733.


Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract. Surgery is the cornerstone of its treatment, although during the last ten years the administration of tyrosine kinase inhibitors (TKI) has become an essential tool as a neoadjuvant and adjuvant strategy in non-wild type GIST. Previous experience has shown that when liver resection is not feasible, liver transplantation (LT) can be considered, although it has not been considered a standard indication for cadaveric LT listing.