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Papers of the Week

2020 Apr

Medicine (Baltimore)



A case report of empty Sella syndrome secondary to Hantaan virus infection and review of the literature.


Chen H, Li Y, Zhang P, Wang Y
Medicine (Baltimore). 2020 Apr; 99(14):e19734.
PMID: 32243412.


Bleeding in the anterior pituitary lobe leading to tissue necrosis occurs in the acute stage of severe clinical forms of hemorrhagic fever with renal syndrome (HFRS), while atrophy of the anterior pituitary lobe with diminution of the gland function occurs after the recovery stage. The relationship between Hantaan virus infection and empty Sella syndrome (ESS) has rarely been reported.