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Papers of the Week

Papers: 28 Mar 2020 - 3 Apr 2020

Animal Studies

2020 Mar 30


Local Sympathectomy Promotes Antiinflammatory Responses and Relief of Paclitaxel-induced Mechanical and Cold Allodynia in Mice.


Tonello R, Xie W, Lee S, Wang M, Liu X, Strong JA, Zhang J-M, Berta T
Anesthesiology. 2020 Mar 30.
PMID: 32235156.


Patients undergoing cancer treatment often experience chemotherapy-induced neuropathic pain at their extremities, for which there is no U.S. Food and Drug Administration-approved drug. The authors hypothesized that local sympathetic blockade, which is used in the clinic to treat various pain conditions, can also be effective to treat chemotherapy-induced neuropathic pain.