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Papers of the Week

Papers: 28 Mar 2020 - 3 Apr 2020

Pharmacology/Drug Development

2020 Apr 02

Curr Pain Headache Rep



Dexmedetomidine in Enhanced Recovery After Surgery (ERAS) Protocols for Postoperative Pain.


Kaye A D, Chernobylsky DJ, Thakur P, Siddaiah H, Kaye RJ, Eng LK, Harbell MW, Lajaunie J, Cornett EM
Curr Pain Headache Rep. 2020 Apr 02; 24(5):21.
PMID: 32240402.


Effective acute pain management has evolved considerably in recent years and is a primary area of focus in attempts to defend against the opioid epidemic. Persistent postsurgical pain (PPP) has an incidence of up to 30-50% and has negative outcome of quality of life and negative burden on individuals, family, and society. The 2016 American Society of Anesthesiologists (ASA) guidelines states that enhanced recovery after surgery (ERAS) forms an integral part of Perioperative Surgical Home (PSH) and is now recommended to use a multimodal opioid-sparing approach for management of postoperative pain. As such, dexmedetomidine is now being used as part of ERAS protocols along with regional nerve blocks and other medications, to create a satisfactory postoperative outcome with reduced opioid consumption in the Post anesthesia care unit (PACU).