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Papers of the Week

Papers: 28 Mar 2020 - 3 Apr 2020

Human Studies

2020 Mar 31

Pain Med

Circulating Adipokines in Predicting the Transition from Acute to Persistent Low Back Pain.


Cytokines such as tumor necrosis factor (TNF) contribute to the transition from acute to persistent pain. Despite increasing incidence of obesity and its linkage with chronic pain and inflammation, cytokines predominantly produced by adipose tissue (adipokines) have received little attention. Here we aimed to explore the longitudinal trajectory of adipokines from the onset of acute low back pain (LBP) and identify combinations of adipokines and/or other features that predict outcome.