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Papers of the Week

2020 Mar 16

Minerva Urol Nefrol

The role of glycosaminoglycans in the management of chronic pelvic pain: a systematic review.


Iacovelli V, Bianchi D, Pletto S, Pacini P, Fede Spicchiale C, Finazzi Agrò E
Minerva Urol Nefrol. 2020 Mar 16.
PMID: 32182229.


Glycosaminoglycans (GAGs) are involved in the pathogenesis of several urologic chronic diseases. Thus, GAGs replenishment therapy is widely reported as a therapeutic tool for chronic pelvic pain (CPP) conditions such as interstitial cystitis/bladder pain syndrome (IC/BPS) and prostate pain syndrome/chronic prostatitis. In this article we reviewed the current status of evidence on the clinic applications of glycosaminoglycans (GAGs) in the CPP.