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Papers of the Week


Papers: 7 Mar 2020 - 13 Mar 2020


Human Studies


2020 Mar 08


BMJ Open


10


3

Central Sensitisation and functioning in patients with chronic low back pain: protocol for a cross-sectional and cohort study.

Authors

Ansuategui Echeita J, Schiphorst Preuper HR, Dekker R, Stuive I, Timmerman H, Wolff AP, Reneman MF
BMJ Open. 2020 Mar 08; 10(3):e031592.
PMID: 32152155.

Abstract

A relevant subsample of patients with chronic low back pain (CLBP) have manifested augmented central pain processing, central sensitisation (CS). Patients with CLBP have limited functioning and participation. Theoretically, physical functioning in patients with CLBP can plausibly be linked to CS; however, evidence to explain such association is scarce. Moreover, there is no gold standard for CS diagnosis. The objectives of the study are: (1) to analyse the association between instruments assessing reference symptoms and signs attributed to CS; (2) to analyse whether reference symptoms and signs attributed to CS are associated with functioning measurement outcomes; and (3) to analyse whether changes (between baseline and discharge) in reference symptoms and signs attributed to CS are related to changes in each of the functioning measurement outcomes.