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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / [Electroacupuncture at “Jiaji” (EX-B2) induced down-regulation of OX-42 and P2X4 in lumbar spinal cord contributes to its analgesic after-effect in rats with chronic constriction injury].

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2020 Jan 25


Zhen Ci Yan Jiu


http://www.ncbi.nlm.nih.gov/pubmed/32144907?dopt=Abstract


45


1

[Electroacupuncture at “Jiaji” (EX-B2) induced down-regulation of OX-42 and P2X4 in lumbar spinal cord contributes to its analgesic after-effect in rats with chronic constriction injury].

Authors

[Electroacupuncture at "Jiaji" (EX-B2) induced down-regulation of OX-42 and P2X4 in lumbar spinal cord contributes to its analgesic after-effect in rats with chronic constriction injury].
Huang H, Chen HE, Yu W, Huang M Y, Wu Q W, Lin L L
Zhen Ci Yan Jiu. 2020 Jan 25; 45(1):40-5.
PMID: 32144907.

Abstract

To investigate the effect of electroacupuncture (EA) at "Jiaji" (EX-B2) at different time points on the expression of OX-42 (a monoclonal antibody with specific expression of complement receptor-3 in spinal microglial cells) and purinergic receptor P2X4 (P2X4) in rats with chronic constriction injury (CCI) of the sciatic nerve, as well as the possible after-effect mechanism of EA analgesia in neuropathic pain.
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