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PLoS One



Continuous wound infiltration versus epidural analgesia for midline abdominal incisions – a randomized-controlled pilot trial (Painless-Pilot trial; DRKS Number: DRKS00008023).


Klotz R, Seide SE, Knebel P, Probst P, Bruckner T, Motsch J, Hyhlik-Dürr A, Böckler D, Larmann J, Diener MK, Weigand MA, Büchler MW, Mihaljevic AL
PLoS One. 2020; 15(3):e0229898.
PMID: 32142529.


To test the feasibility of a randomized controlled study design comparing epidural analgesia (EDA) with continuous wound infiltration (CWI) in respect to postoperative complications and mobility to design a future multicentre randomized controlled trial.