I am a
Home I AM A Search Login

Papers of the Week

Papers: 29 Feb 2020 - 6 Mar 2020

Pharmacology/Drug Development


2020 Mar 02

Expert Opin Drug Saf

A comprehensive overview and safety evaluation of fremanezumab as a preventive therapy for migraine.


Parikh SK, Burkett JG, Silberstein SD
Expert Opin Drug Saf. 2020 Mar 02.
PMID: 32116061.


: Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP mAb), is a migraine-specific treatment for migraine prevention.: This review will briefly discuss other available and emerging CGRP mAbs and the neurophysiology of fremanezumab. The review will focus on phase III trials of the efficacy of fremanezumab for episodic and chronic trials, and a recent pooled safety and tolerability analysis of its use.: Continued efficacy and safety data collection will help guide long-term risk and efficacy counseling in the general population.