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Papers of the Week

Papers: 22 Feb 2020 - 28 Feb 2020

2020 Feb 25

Cell Mol Neurobiol

The Role of the Spinal Wnt Signaling Pathway in HIV-Related Neuropathic Pain.


Huang J, Bloe C B, Zhou X, Wu S, Zhang W
Cell Mol Neurobiol. 2020 Feb 25.
PMID: 32100186.


Human immunodeficiency virus (HIV)-related neuropathic pain includes HIV-induced neuropathic pain (HNP) and antiretroviral therapy-induced neuropathic pain (ART-NP). A significant amount of evidence from the past few years has shown that the development of HIV-related neuropathic pain is closely related to the activation of the Wnt signaling pathway in the spinal cord. This review summarizes the function of the spinal Wnt signaling pathway in HIV-induced neuropathic pain, focusing on the role of the spinal Wnt signaling pathway in HNP, and provides a theoretical basis for further studies and the exploration of new target drugs.