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Papers of the Week

2020 Feb 17


Brainstem Atrophy in Gulf War Illness.


Zhang Y, Avery T, Vakhtin AA, Mathersul DC, Tranvinh E, Wintermark M, Massaband P, Ashford WJ, Bayley PJ, Furst AJ
Neurotoxicology. 2020 Feb 17.
PMID: 32081703.


Gulf War illness (GWI) is a condition that affects about 30% of veterans who served in the 1990-91 Persian Gulf War. Given its broad symptomatic manifestation, including chronic pain, fatigue, neurological, gastrointestinal, respiratory, and skin problems, it is of interest to examine whether GWI is associated with changes in the brain. Existing neuroimaging studies, however, have been limited by small sample sizes, inconsistent GWI diagnosis criteria, and potential comorbidity confounds.