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Papers of the Week

2020 Feb 20

Acad Emerg Med

Randomized Clinical Trial of IV Acetaminophen as an Adjunct to IV Hydromorphone for Acute Severe Pain in Emergency Department Patients.


Bijur PE, Friedman BW, White D, Wollowitz A, Campbell C, Jones M, Chang AK, Gallagher JE
Acad Emerg Med. 2020 Feb 20.
PMID: 32077553.


A fundamental challenge for Emergency Department (ED) clinicians is to relieve severe, acute pain while simultaneously avoiding adverse events associated with opioid analgesics. Because there is evidence that intravenous (IV) acetaminophen is an effective adjuvant analgesic in post-operative settings, we examined whether it also has a role in the ED.