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Papers of the Week


Papers: 15 Feb 2020 - 21 Feb 2020


Human Studies

PAIN TYPE:
Migraine/Headache


2020 Feb 17


Headache

Neuromelanin Locus Coeruleus MRI Contrast in Migraine With Aura.

Authors

Gollion C, Arribarat G, Ruidavets J-B, Fabre N, Barège M, Bonneville F, Larrue V, Peran P
Headache. 2020 Feb 17.
PMID: 32065391.

Abstract

The locus coeruleus (LC) is one of the brainstem nuclei that may be activated during migraine attack. As LC contains neuromelanin, a by-product of norepinephrine synthesis, it can be delineated in vivo using neuromelanin sensitive magnetic resonance imaging (MRI). The neuromelanin content in LC has been suggested to reflect previous LC activation. We investigated LC MRI contrast in patients with migraine with aura (MWA) and its correlation with migraine features.