I am a
Home I AM A Search Login

Papers of the Week

Papers: 15 Feb 2020 - 21 Feb 2020

Human Studies


2020 Feb 17


Neuromelanin Locus Coeruleus MRI Contrast in Migraine With Aura.


Gollion C, Arribarat G, Ruidavets J-B, Fabre N, Barège M, Bonneville F, Larrue V, Peran P
Headache. 2020 Feb 17.
PMID: 32065391.


The locus coeruleus (LC) is one of the brainstem nuclei that may be activated during migraine attack. As LC contains neuromelanin, a by-product of norepinephrine synthesis, it can be delineated in vivo using neuromelanin sensitive magnetic resonance imaging (MRI). The neuromelanin content in LC has been suggested to reflect previous LC activation. We investigated LC MRI contrast in patients with migraine with aura (MWA) and its correlation with migraine features.