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Papers of the Week


2020 Feb 13


J Orthop Surg Res


15


1

Umbilical cord-derived Wharton’s jelly for regenerative medicine applications.

Authors

Gupta A, El-Amin SF, Levy HJ, Sze-Tu R, Ibim SE, Maffulli N
J Orthop Surg Res. 2020 Feb 13; 15(1):49.
PMID: 32054483.

Abstract

The last decade has seen an explosion in the interest in using biologics for regenerative medicine applications, including umbilical cord-derived Wharton's Jelly. There is insufficient literature assessing the amount of growth factors, cytokines, hyaluronic acid, and extracellular vesicles including exosomes in these products. The present study reports the development of a novel Wharton's jelly formulation and evaluates the presence of growth factors, cytokines, hyaluronic acid, and extracellular vesicles including exosomes.