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Papers of the Week

Papers: 15 Feb 2020 - 21 Feb 2020

Human Studies


2020 Feb 14


Mitochondrial genome-wide association study of migraine – the HUNT Study.


Børte S, Zwart J-A, Skogholt A H, Gabrielsen M E, Thomas LF, Fritsche LG, Surakka I, Nielsen JB, Zhou W, Wolford BN, Vigeland MD, Hagen K, Kristoffersen E S, Nyholt DR, Chasman DI, Brumpton BM, Willer CJ, Winsvold BS
Cephalalgia. 2020 Feb 14:333102420906835.
PMID: 32056457.


Variation in mitochondrial DNA (mtDNA) has been indicated in migraine pathogenesis, but genetic studies to date have focused on candidate variants, with sparse findings. We aimed to perform the first mitochondrial genome-wide association study of migraine, examining both single variants and mitochondrial haplogroups.