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Papers of the Week

2020 Jan 23

J Affect Disord


Minimally important differences and severity thresholds are estimated for the PROMIS depression scales from three randomized clinical trials.


Kroenke K, Stump TE, Chen CX, Kean J, Bair MJ, Damush TM, Krebs EE, Monahan PO
J Affect Disord. 2020 Jan 23; 266:100-108.
PMID: 32056864.


Patient Reported Outcomes Measurement Information Systems (PROMIS) scales are increasingly being used to measure symptoms in research and practice. The purpose of this study was to determine the minimally important difference (MID) and severity thresholds (cut-points) for the four fixed-length PROMIS depression scales.