Papers of the Week

There exists a limited number of studies investigating the correlation between spinal adenosine A1 receptors and Vincristine-induced peripheral neuropathy (VIPN). This study explored the role of intrathecal N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) in neuropathic pain induced in rats by administering vincristine (100 μg/kg i.p.) for 10 days (two 5-day cycles with a 2-day pause).