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Papers of the Week

Papers: 8 Feb 2020 - 14 Feb 2020


Animal Studies

2020 Feb 07

Brain Res

Electroacupuncture suppresses the pain and pain-related anxiety of chronic inflammation in rats by increasing the expression of the NPS/NPSR system in the ACC.


Du J, Fang J, Xu Z, Xiang X, Wang S, Sun H, Shao X, Jiang Y, Liu B, Fang J
Brain Res. 2020 Feb 07:146719.
PMID: 32044336.


The neuropeptide S/neuropeptide S receptor (NPS/NPSR) system is involved in the regulation of anxiety in rodents. Chronic inflammation can induce anxiety. Our lab has observed that electroacupuncture (EA) has a beneficial effect on chronic inflammatory pain and pain-related anxiety; however, the mechanism should be further clarified. In the present study, we used an inflammatory pain model to investigate the role of the NPS/NPSR system in the anterior cingulate cortex (ACC) in the analgesic and antianxiety effects of EA.