I am a
Home I AM A Search Login

Papers of the Week

2020 Jan-Feb

G Chir



Retroperitoneal sarcomas: from diagnosis to treatment. Case series and review of the literature.


Mantas D, Garmpis N, Polychroni D, Garpi A, Damaskos C, Liakea A, Sypsa G, Kouskos E
G Chir. 2020 Jan-Feb; 41(1):18-33.
PMID: 32038009.


Retroperitoneal sarcoma is a rare malignancy arising from mesenchymal cells, most commonly presented as an abdominal mass and is associated with poor prognosis. The most effective treatment modality for retroperitoneal sarcomas is complete surgical resection, including sometimes adjacent organs infiltrated by the tumor. Radiotherapy is frequently applied and has shown some benefit, while the role of chemotherapy and molecular-targeted agents is still not clear. Local recurrence is common for retroperitoneal sarcomas and still remains the main cause of death. The major factors associated with the overall survival are tumor grade, histological subtype, complete macroscopic excision and multifocality.