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Papers of the Week

2020 Feb 08

J Vet Intern Med

Plasma disposition of gabapentin after the intragastric administration of escalating doses to adult horses.


Gold JR, Grubb TL, Green S, Cox S, Villarino NF
J Vet Intern Med. 2020 Feb 08.
PMID: 32034928.


In humans, gabapentin an analgesic, undergoes non-proportional pharmacokinetics which can alter efficacy. No information exists on the pharmacokinetics of dosages >20 mg/kg, escalating dosages or dose proportionality of gabapentin in horses.