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Papers of the Week

2020 Feb 05

BMC Neurol



Improving symptom burden in adults with persistent post-concussive symptoms: a randomized aerobic exercise trial protocol.


Mercier LJ, Fung TS, Harris AD, Dukelow SP, Debert CT
BMC Neurol. 2020 Feb 05; 20(1):46.
PMID: 32024486.


Persistent post-concussive symptoms (PPCS) affect up to 30% of individuals following mild traumatic brain injury. PPCS frequently includes exercise intolerance. Sub-symptom threshold aerobic exercise has been proposed as a treatment option for symptom burden and exercise intolerance in this population. The primary aim of this study is to evaluate whether a progressive, sub-symptom threshold aerobic exercise program can alleviate symptom burden in adults with PPCS.