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Papers of the Week

2020 May

Psychopharmacology (Berl)



Eslicarbazepine acetate interacts in a beneficial manner with standard and alternative analgesics to reduce trigeminal nociception.


Pecikoza U, Tomić M, Micov A, Vuković M, Stepanović-Petrović R
Psychopharmacology (Berl). 2020 May; 237(5):1435-1446.
PMID: 32025776.


Acute pain states in the trigeminal region (headaches, dental pain) fall into the most prevalent painful conditions. Standard analgesics (paracetamol/NSAIDs) represent the cornerstone of their treatment, whereas triptans are primarily used in migraine attacks. Due to limited efficacy and/or side effects of current treatments, identifying favorable combinations of available drugs is justified.