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Papers of the Week

2020 Mar

Int J Surg


Topical 5% Minoxidil versus Topical 0.2% Glyceryl Trinitrate in Treatment of Chronic Anal Fissure: A Randomized Clinical Trial.


Emile S H, Abdel-Razik M A, Elshobaky A, Elbaz S A, Khafagy W, Shalaby M
Int J Surg. 2020 Mar; 75:152-158.
PMID: 32028023.


Chronic anal fissure (CAF) is a common painful anal condition. Medical treatment of CAF involves the use of agents that induce chemical sphincterotomy. The present trial aimed to compare the efficacy and safety of topical minoxidil and glyceryl trinitrate (GTN) preparations in treatment of CAF.