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Papers of the Week

2018 Oct 03

JA Clin Rep



Anesthetic management of a patient with congenital insensitivity to pain with anhidrosis by coadministration of remifentanil.


Takeuchi Y, Fujita Y, Shimomura T, Kurokawa S, Noguchi H, Fujiwara Y
JA Clin Rep. 2018 Oct 03; 4(1):72.
PMID: 32025911.


Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disease characterized by unexplained fever, systemic insensitivity to pain, anhidrosis, and mental distress. Anesthetic management is challenging because autonomic dysfunction can induce perioperative complications. Only a few reports of anesthetic management of CIPA patients have been published. We herein present a case of successful management of the same patient on two occasions using small doses of fentanyl and remifentanil.