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Papers of the Week
Evidence of the involvement of spinal αB-crystallin in the maintenance of bone cancer pain in rats.
Abstract
αB-crystallin (CRYAB) is a small heat shock protein that is able to inhibit neuroinflammatory responses under various pathological conditions. Some studies have proven that neuroinflammatory mechanisms play important roles in bone cancer pain (BCP). However, whether CRYAB participates in the maintenance of BCP has not yet been examined.