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2020 07

Acta Anaesthesiol Scand



Effects of low-dose remifentanil infusion on analgesic or antiemetic requirement during brain function mapping: a retrospective cohort study.


Shiraki A, Goto W, Fukagawa H, Arakawa Y, Kikuchi T, Mineharu Y, Yamao Y, Yasuda T, Hattori E, Fukui A, Matsui Y, Yonezawa A, Furukawa K, Mizota T
Acta Anaesthesiol Scand. 2020 07; 64(6):735-741.
PMID: 31997302.


Pain and discomfort during the awake phase in awake craniotomy should be relieved to facilitate brain mapping. Although some anaesthesiologists use low-dose (0.01-0.05µg/kg/min) remifentanil infusion to provide analgesia during this phase, its efficacy and side effects have never been evaluated. Therefore, this study primarily aimed to investigate the effects of low-dose remifentanil infusion on the need for antiemetic treatment during brain mapping and secondarily aimed to determine its effects on the need for additional analgesic treatment.