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Papers of the Week

Papers: 25 Jan 2020 - 31 Jan 2020

Human Studies

2020 06

Br J Pharmacol



Functional expression and pharmacological modulation of TRPM3 in human sensory neurons.


Vangeel L, Benoit M, Miron Y, Miller PE, De Clercq K, Chaltin P, Verfaillie C, Vriens J, Voets T
Br J Pharmacol. 2020 06; 177(12):2683-2695.
PMID: 31985045.


The transient receptor potential (TRP) ion channel TRPM3 functions as a noxious heat sensor and plays a key role in acute pain sensation and inflammatory hyperalgesia in rodents. Despite its potential as novel analgesic drug target, little is known about the expression, function and modulation of TRPM3 in the human somatosensory system.