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Papers of the Week

Papers: 25 Jan 2020 - 31 Jan 2020

Human Studies

2020 04

Clin J Pain



Serum Inflammatory Markers in Patients with Knee Osteoarthritis: A Proteomic Approach.


Giordano R, Petersen K K, Andersen H H, Simonsen O, Arendt-Nielsen L
Clin J Pain. 2020 04; 36(4):229-237.
PMID: 31977377.


Osteoarthritis (OA) is known to be a slowly progressive disease that alters all tissue compartments of the joint involved with a characteristic degradation of the cartilage, bone remodeling, and inflammation. One of the prominent symptoms in OA patients is pain, but a few radiological, inflammatory or structurally related biomarkers have shown little if any associations to pain. This study aimed to assess serum levels of 92 markers involved in inflammatory pathways in patients with knee OA (KOA) and evaluate their possible associations with the clinical pain intensity.