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Papers: 18 Jan 2020 - 24 Jan 2020
Animal Studies, Pharmacology/Drug Development
2020 05
Br J Pharmacol
177
10
The midbrain periaqueductal grey (PAG) plays a central role in modulating pain through a descending pathway that projects indirectly to the spinal cord via the rostroventral medial medulla (RVM). While opioids are potent analgesics that target the PAG, their cellular actions on descending projection neurons are unclear.