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Papers of the Week

Papers: 18 Jan 2020 - 24 Jan 2020

Human Studies

2020 01 21




Effect of Early Surgery vs Endoscopy-First Approach on Pain in Patients With Chronic Pancreatitis: The ESCAPE Randomized Clinical Trial.


Issa Y, Kempeneers MA, Bruno MJ, Fockens P, Poley J-W, Ahmed Ali U, Bollen TL, Busch OR, Dejong CH, van Duijvendijk P, van Dullemen HM, van Eijck CH, van Goor H, Hadithi M, Haveman J-W, Keulemans Y, Nieuwenhuijs VB, Poen AC, Rauws EA, Tan AC, et al.
JAMA. 2020 01 21; 323(3):237-247.
PMID: 31961419.


For patients with painful chronic pancreatitis, surgical treatment is postponed until medical and endoscopic treatment have failed. Observational studies have suggested that earlier surgery could mitigate disease progression, providing better pain control and preserving pancreatic function.