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Papers of the Week

Papers: 11 Jan 2020 - 17 Jan 2020

Human Studies

2020 02

Ann Neurol



Restoration of Somatosensory Function by Pairing Vagus Nerve Stimulation with Tactile Rehabilitation.


Darrow MJ, Mian TM, Torres M, Haider Z, Danaphongse T, Rennaker RL, Kilgard MP, Hays SA
Ann Neurol. 2020 02; 87(2):194-205.
PMID: 31875975.


Sensory dysfunction is a common consequence of many forms of neurological injury, including stroke and nerve damage. Rehabilitative paradigms that incorporate sensory retraining can provide modest benefits, but the majority of patients are left with lasting sensory loss. We have developed a novel strategy that uses closed-loop vagus nerve stimulation (VNS) paired with tactile rehabilitation to enhance synaptic plasticity and facilitate recovery of sensory function.