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Papers of the Week


Papers: 11 Jan 2020 - 17 Jan 2020


Human Studies


2020 07


Cephalalgia


40


8

Familial trigeminal neuralgia – a systematic clinical study with a genomic screen of the neuronal electrogenisome.

Authors

Di Stefano G, Yuan J-H, Cruccu G, Waxman SG, Dib-Hajj SD, Truini A
Cephalalgia. 2020 07; 40(8):767-777.
PMID: 31928344.

Abstract

This cross-sectional study examined, for the first time, a large cohort of patients with trigeminal neuralgia, to ascertain the occurrence of familial cases, providing a systematic description of clinical features of familial disease. Since there is evidence linking hyperexcitability of trigeminal ganglion neurons to trigeminal neuralgia, we also carried out an exploratory genetic analysis of the neuronal electrogenisome in these patients.