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Papers of the Week

2019 Oct-Dec

J Anaesthesiol Clin Pharmacol



Opioid-free anesthesia for breast cancer surgery: A comparison of ultrasound guided paravertebral and pectoral nerve blocks. A randomized controlled trial.


Tripathy S, Mandal I, Rao P B, Panda A, Mishra T, Kar M
J Anaesthesiol Clin Pharmacol. 2019 Oct-Dec; 35(4):475-480.
PMID: 31920230.


Pectoral block (PECS)-based anesthesia without opioids decreases analgesic requirement, pain scores and post-operative nausea vomiting (PONV) compared to conventional opioid-based general anesthesia in patients undergoing modified radical mastectomy and axillary dissection (MRM-AD). We compared PECS versus Paravertebral Block (PVB) in providing an opioid free, nerve block-based regimen. Outcomes of interest were post-operative analgesic requirement, duration of analgesia, PONV and patient and surgeon satisfaction.