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Papers of the Week


2020 Mar


Lancet Infect Dis


20


3

Xpert MTB/RIF Ultra for the diagnosis of HIV-associated tuberculous meningitis: a prospective validation study.

Authors

Cresswell FV, Tugume L, Bahr NC, Kwizera R, Bangdiwala AS, Musubire AK, Rutakingirwa M, Kagimu E, Nuwagira E, Mpoza E, Rhein J, Williams DA, Muzoora C, Grint D, Elliott AM, Meya DB, Boulware DR
Lancet Infect Dis. 2020 Mar; 20(3):308-317.
PMID: 31924549.

Abstract

Tuberculous meningitis accounts for 1-5% of tuberculosis cases. Diagnostic delay contributes to poor outcomes. We evaluated the performance of the new Xpert MTB/RIF Ultra (Xpert Ultra) for tuberculous meningitis diagnosis.